STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAD17Cell cycle checkpoint protein RAD17 isoform X1. (682 aa)    
Predicted Functional Partners:
RFC2
Replication factor C subunit 2/4.
    
 0.999
RFC4
Replication factor C subunit 4 isoform X1.
   
 0.997
RFC3
Replication factor C subunit 3 isoform X1.
   
 0.997
RFC5
Replication factor C subunit 3/5.
   
0.997
HUS1
Checkpoint protein HUS1 isoform X1.
   
 0.992
RAD1
Cell cycle checkpoint protein RAD1.
   
 0.980
RAD9A
Cell cycle checkpoint control protein RAD9A isoform X1.
   
 0.977
WRN
Werner syndrome ATP-dependent helicase isoform X1.
   
 0.963
RAD9B
Cell cycle checkpoint control protein RAD9B isoform X1.
   
 0.949
TOPBP1
DNA topoisomerase 2-binding protein 1 isoform X1.
   
 0.933
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.