STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NHEJ1Non-homologous end-joining factor 1 isoform X1. (299 aa)    
Predicted Functional Partners:
XRCC5
X-ray repair cross-complementing protein 5 isoform X1.
    
 0.975
LIG4
DNA ligase 4.
    
 0.975
PRKDC
DNA-dependent protein kinase catalytic subunit isoform X1.
    
 0.925
XRCC6
X-ray repair cross-complementing protein 6 isoform X1.
    
 0.923
DCLRE1C
DNA cross-link repair 1C protein.
   
 
 0.737
POLL
DNA polymerase lambda.
     
 0.720
XRCC4
DNA repair protein XRCC4.
     
 0.678
POLM
DNA-directed DNA/RNA polymerase mu isoform X1.
     
 0.639
ALPK1
Alpha-protein kinase 1 isoform X1.
      
 0.619
AGMO
Alkylglycerol monooxygenase isoform X1.
      
 0.612
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.