STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TYMSThymidylate synthase. (313 aa)    
Predicted Functional Partners:
DHFR
Dihydrofolate reductase.
 
 
 0.995
SHMT1
Serine hydroxymethyltransferase, cytosolic.
  
 
 0.988
DTYMK
Thymidylate kinase.
  
 
 0.987
SHMT2
Serine hydroxymethyltransferase, mitochondrial.
  
 
 0.987
LOC109273815
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like.
  
 0.986
DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1.
  
 0.986
MTHFD2L
Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase.
  
 
 0.984
MTHFD2
Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase.
  
 
 0.984
DCTD
Deoxycytidylate deaminase.
  
 
 0.984
FPGS
Folylpolyglutamate synthase, mitochondrial isoform X1.
     
 0.974
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.