STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSD17B617-beta-hydroxysteroid dehydrogenase type 6. (317 aa)    
Predicted Functional Partners:
LRAT
Phosphatidylcholine-retinol O-acyltransferase.
     
 0.923
SDR16C5
All-trans-retinol dehydrogenase (NAD+).
  
 
0.922
HSD17B8
Estradiol 17-beta-dehydrogenase 8.
  
 
0.921
SRD5A1
3-oxo-5-alpha-steroid 4-dehydrogenase 1.
   
 
 0.919
CYP26A1
Cytochrome P450 family 26 subfamily A.
   
 0.918
BCO1
Beta,beta-carotene 15,15'-dioxygenase isoform X1.
   
 
 0.916
LOC109272160
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase.
   
 
 0.914
ALDH1A1
Retinal dehydrogenase 1.
   
 
 0.910
HSD17B2
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+).
  
 
 
0.909
AKR1D1
3-oxo-5-beta-steroid 4-dehydrogenase isoform X1.
   
 
 0.908
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.