STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIRT3NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X1. (257 aa)    
Predicted Functional Partners:
NMNAT2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 isoform X1.
    
 0.963
NAMPT
Nicotinamide phosphoribosyltransferase.
     
 0.958
NADSYN1
Glutamine-dependent NAD(+) synthetase isoform X1.
    
 0.932
NMNAT1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1.
    
 0.931
FOXO3
Forkhead box protein O3.
    
 0.930
ACSS1
Acetyl-coenzyme A synthetase 2-like, mitochondrial isoform X1.
    
 0.924
NADK
NAD kinase isoform X1.
  
 
 0.921
CD38
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 isoform X1.
     
 0.916
NUDT12
Peroxisomal NADH pyrophosphatase NUDT12.
    
 0.913
NNT
NAD(P) transhydrogenase, mitochondrial isoform X1.
   
 
 0.911
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.