STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTPHomeobox protein orthopedia. (325 aa)    
Predicted Functional Partners:
SIM1
Single-minded homolog 1 isoform X1.
   
  
 0.539
SP6
Transcription factor Sp6.
   
 
 0.516
ARNT2
Aryl hydrocarbon receptor nuclear translocator 2.
    
 
 0.515
DMRT3
Doublesex- and mab-3-related transcription factor 3.
    
 
 0.475
NHLH1
Nescient helix-loop-helix protein.
   
 0.471
NHLH2
Nescient helix-loop-helix protein.
   
 0.471
DLX1
Homeobox protein DLX-1 isoform X1.
   
  
0.468
GBX1
Homeobox protein GBX-1.
    
0.456
VAX1
LOW QUALITY PROTEIN: ventral anterior homeobox 1.
   
  
0.454
PLAGL1
Zinc finger protein PLAGL1 isoform X1.
   
 
 0.451
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.