STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLP2Proteolipid protein 2. (152 aa)    
Predicted Functional Partners:
PLP1
Myelin proteolipid protein isoform X1.
   
 
 0.952
IRF3
Interferon regulatory factor 3 isoform X1.
      
 0.512
SIPA1
Signal-induced proliferation-associated protein 1 isoform X1.
      
 0.508
PPP1CA
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit.
      
 0.503
THAP11
THAP domain-containing protein 11.
      
 0.503
TPD52L2
Tumor protein D54 isoform X1.
   
 
 0.460
IFNB1
Interferon beta.
   
  
 0.443
ZUP1
Zinc finger with UFM1-specific peptidase domain protein isoform X1.
      
 0.438
ISG15
Ubiquitin cross-reactive protein.
      
 0.436
IKBKG
Inhibitor of nuclear factor kappa-B kinase subunit gamma.
   
  
 0.422
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.