STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IPO8Importin-8 isoform X1. (1037 aa)    
Predicted Functional Partners:
RAN
GTP-binding nuclear protein Ran.
   
 0.889
AGO2
Eukaryotic translation initiation factor 2C.
    
 0.883
KPNB1
Importin subunit beta-1.
   
 
 0.880
TTC37
Tetratricopeptide repeat protein 37.
   
 0.825
PES1
Pescadillo homolog isoform X1.
   
 
 0.813
EXOSC10
Exosome complex exonuclease RRP6.
   
 0.807
EXOSC1
Exosome component 1.
   
 0.791
EXOSC7
Exosome complex component RRP42.
   
 0.791
EXOSC2
Exosome complex component RRP4.
   
 0.787
FAU
Ubiquitin-like protein fubi and ribosomal protein S30 isoform X1.
    
  0.778
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.