STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOX4Transcription factor SOX4 (SOX group C). (477 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 0.664
POU5F1
POU domain, class 5, transcription factor 1.
    
 0.608
ENSPPRP00000018515
annotation not available
    
 0.608
SOX17
Transcription factor SOX17 (SOX group F).
     
0.590
TCF7
Transcription factor 7.
    
0.560
EZH2
Histone-lysine N-methyltransferase EZH2 isoform X1.
    
 
 0.535
ATOH7
Protein atonal homolog 7.
      
 0.534
DONSON
Protein downstream neighbor of Son isoform X1.
      
 0.513
LEF1
Lymphoid enhancer-binding factor 1 isoform X1.
    
 0.499
SOX8
SRY-box transcription factor 8.
     
0.490
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.