STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAPN8Calpain-8. (420 aa)    
Predicted Functional Partners:
CAPNS1
Calpain small subunit 1 isoform X1.
 
 
 0.864
CAST
Calpastatin isoform X1.
   
 0.817
PLAU
Urokinase-type plasminogen activator isoform X1.
   
 
 0.621
ITSN2
Intersectin-2 isoform X1.
   
 
 0.603
TXN2
Thioredoxin, mitochondrial.
   
 
 0.522
ERCC3
TFIIH basal transcription factor complex helicase XPB subunit.
   
  
 0.516
ENSPPRP00000025194
annotation not available
      
 0.513
COLQ
Acetylcholinesterase collagenic tail peptide isoform X1.
    
 0.511
ATF4
Cyclic AMP-dependent transcription factor ATF-4.
      
 0.508
LRGUK
Leucine-rich repeat and guanylate kinase domain-containing protein isoform X1.
   
 
 0.482
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.