STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPC3Glypican-3 isoform X1. (580 aa)    
Predicted Functional Partners:
SHH
Sonic hedgehog protein.
    
 0.948
IHH
Indian hedgehog protein isoform X1.
    
 0.948
IGF2
Insulin-like growth factor II isoform X1.
   
 
 0.943
WNT6
Wingless-type MMTV integration site family, member 6.
    
 0.928
LOC109259603
Wingless-type MMTV integration site family, member 3.
    
 0.923
WNT3
Wingless-type MMTV integration site family, member 3.
    
 0.923
WNT5A
Wingless-type MMTV integration site family, member 5.
    
 0.920
WNT5B
Wingless-type MMTV integration site family, member 5.
    
 0.920
WNT4
Wingless-type MMTV integration site family, member 4.
    
 0.918
WNT2
Wingless-type MMTV integration site family, member 2.
    
 0.917
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.