STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UHRF2E3 ubiquitin-protein ligase UHRF2. (803 aa)    
Predicted Functional Partners:
DNMT1
DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
 0.893
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
   0.865
PCNP
PEST proteolytic signal-containing nuclear protein.
    
 
 0.720
USP7
Ubiquitin carboxyl-terminal hydrolase 7 isoform X2; Belongs to the peptidase C19 family.
    
 
 0.704
TMEM109
Transmembrane protein 109.
    
 
 0.701
ZCCHC24
Zinc finger CCHC domain-containing protein 24.
      
 0.675
LIG1
DNA ligase.
   
 
 0.659
RNF34
E3 ubiquitin-protein ligase RNF34 isoform X1.
      
 0.651
ZNF131
Zinc finger protein 131.
    
 0.651
ARMC1
Armadillo repeat-containing protein 1.
   
  
 0.634
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
Server load: low (24%) [HD]