STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC12A3Solute carrier family 12 member 3 isoform X1. (1030 aa)    
Predicted Functional Partners:
WNK4
Serine/threonine-protein kinase WNK4 isoform X1.
    
 
 0.791
SLC5A2
Sodium/glucose cotransporter 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.775
WNK1
Serine/threonine-protein kinase WNK1 isoform X1.
    
 
 0.737
KLHL2
Kelch-like protein 2 isoform X1.
    
 
 0.716
TRPM6
Transient receptor potential cation channel subfamily M member 6 isoform X1.
      
 0.708
CLDN16
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  
 0.669
NPHS2
Podocin.
   
 
 0.654
SCNN1B
Amiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
   
  
 0.646
KLHL3
Kelch-like protein 3.
    
 
 0.640
SLC34A1
Sodium-dependent phosphate transport protein 2A.
  
  
 0.613
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.