STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2B3SH2B adapter protein 3. (578 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2 isoform X1.
    
 0.942
NTRK3
Tyrosine-protein kinase receptor.
    
 0.919
NTRK1
Tyrosine-protein kinase receptor.
    
 0.919
NTRK2
Tyrosine-protein kinase receptor.
    
 0.919
SH2B1
SH2B adapter protein 1 isoform X1.
    
0.909
KITLG
Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.
     
 0.754
JAK2
Tyrosine-protein kinase.
    
 0.722
SETBP1
SET-binding protein.
      
 0.709
SRSF2
Serine/arginine-rich splicing factor 2.
      
 0.616
CCDC92
Coiled-coil domain-containing protein 92.
      
 0.615
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.