node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HSPA9 | LOC101367407 | A0A2U3VRM1 | A0A2U3Z9K3 | Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. | Uncharacterized protein LOC101367407. | 0.906 |
HSPA9 | TLR1 | A0A2U3VRM1 | A0A2U3VMS6 | Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. | Toll-like receptor 1; Belongs to the Toll-like receptor family. | 0.906 |
HSPA9 | TLR2 | A0A2U3VRM1 | A0A2U3VHM7 | Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. | Toll-like receptor 2; Belongs to the Toll-like receptor family. | 0.906 |
HSPA9 | TLR4 | A0A2U3VRM1 | A0A2U3X221 | Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. | Toll-like receptor 4; Belongs to the Toll-like receptor family. | 0.906 |
HSPA9 | TLR6 | A0A2U3VRM1 | A0A2U3ZBH5 | Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. | Toll-like receptor 6; Belongs to the Toll-like receptor family. | 0.906 |
IL1B | IL6 | A0A2U3VWQ9 | A0A2U3VQB3 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-6 isoform X1. | 0.914 |
IL1B | LOC101367407 | A0A2U3VWQ9 | A0A2U3Z9K3 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Uncharacterized protein LOC101367407. | 0.659 |
IL1B | LY96 | A0A2U3VWQ9 | A0A2U3W6Y1 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Lymphocyte antigen 96. | 0.554 |
IL1B | MYD88 | A0A2U3VWQ9 | A0A2U3WSQ4 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. | 0.862 |
IL1B | TLR1 | A0A2U3VWQ9 | A0A2U3VMS6 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Toll-like receptor 1; Belongs to the Toll-like receptor family. | 0.698 |
IL1B | TLR2 | A0A2U3VWQ9 | A0A2U3VHM7 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Toll-like receptor 2; Belongs to the Toll-like receptor family. | 0.659 |
IL1B | TLR4 | A0A2U3VWQ9 | A0A2U3X221 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Toll-like receptor 4; Belongs to the Toll-like receptor family. | 0.857 |
IL1B | TLR6 | A0A2U3VWQ9 | A0A2U3ZBH5 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Toll-like receptor 6; Belongs to the Toll-like receptor family. | 0.881 |
IL1B | TNF | A0A2U3VWQ9 | A0A2U3X072 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Tumor necrosis factor; Belongs to the tumor necrosis factor family. | 0.935 |
IL6 | IL1B | A0A2U3VQB3 | A0A2U3VWQ9 | Interleukin-6 isoform X1. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.914 |
IL6 | LOC101367407 | A0A2U3VQB3 | A0A2U3Z9K3 | Interleukin-6 isoform X1. | Uncharacterized protein LOC101367407. | 0.659 |
IL6 | LY96 | A0A2U3VQB3 | A0A2U3W6Y1 | Interleukin-6 isoform X1. | Lymphocyte antigen 96. | 0.559 |
IL6 | MYD88 | A0A2U3VQB3 | A0A2U3WSQ4 | Interleukin-6 isoform X1. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. | 0.760 |
IL6 | TLR1 | A0A2U3VQB3 | A0A2U3VMS6 | Interleukin-6 isoform X1. | Toll-like receptor 1; Belongs to the Toll-like receptor family. | 0.768 |
IL6 | TLR2 | A0A2U3VQB3 | A0A2U3VHM7 | Interleukin-6 isoform X1. | Toll-like receptor 2; Belongs to the Toll-like receptor family. | 0.659 |