STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3BP2LOW QUALITY PROTEIN: SH3 domain-binding protein 2. (601 aa)    
Predicted Functional Partners:
VAV1
Proto-oncogene vav isoform X1.
   
 0.968
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.944
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.941
VAV3
Guanine nucleotide exchange factor VAV3 isoform X1.
   
 0.934
VAV2
Guanine nucleotide exchange factor VAV2 isoform X1.
   
 0.934
TNKS2
Poly [ADP-ribose] polymerase.
    
 
 0.910
TNKS
Poly [ADP-ribose] polymerase.
    
 
 0.731
HDDC3
guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase MESH1.
      
 0.614
SYK
Tyrosine-protein kinase.
    
 
 0.569
GABARAPL1
Gamma-aminobutyric acid receptor-associated protein-like 1.
      
 0.526
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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