node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CXCR5 | ICOS | A0A2U3WTG3 | A0A2U3WFU9 | C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Inducible T-cell costimulator. | 0.779 |
CXCR5 | IFNG | A0A2U3WTG3 | A0A2U3X2V9 | C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.622 |
CXCR5 | IL21 | A0A2U3WTG3 | A0A2U3W0Y3 | C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Interleukin; Belongs to the IL-15/IL-21 family. | 0.602 |
CXCR5 | IL21R | A0A2U3WTG3 | A0A2U3VQ60 | C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Interleukin-21 receptor. | 0.882 |
CXCR5 | IL6 | A0A2U3WTG3 | A0A2U3VQB3 | C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Interleukin-6 isoform X1. | 0.523 |
CXCR5 | JAK3 | A0A2U3WTG3 | A0A2U3W8S8 | C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | Tyrosine-protein kinase. | 0.666 |
ICOS | CXCR5 | A0A2U3WFU9 | A0A2U3WTG3 | Inducible T-cell costimulator. | C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | 0.779 |
ICOS | IFNG | A0A2U3WFU9 | A0A2U3X2V9 | Inducible T-cell costimulator. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.690 |
ICOS | IL21 | A0A2U3WFU9 | A0A2U3W0Y3 | Inducible T-cell costimulator. | Interleukin; Belongs to the IL-15/IL-21 family. | 0.688 |
ICOS | IL21R | A0A2U3WFU9 | A0A2U3VQ60 | Inducible T-cell costimulator. | Interleukin-21 receptor. | 0.898 |
ICOS | IL6 | A0A2U3WFU9 | A0A2U3VQB3 | Inducible T-cell costimulator. | Interleukin-6 isoform X1. | 0.725 |
ICOS | STAT3 | A0A2U3WFU9 | A0A2U3WNF0 | Inducible T-cell costimulator. | Signal transducer and activator of transcription. | 0.548 |
IFNG | CXCR5 | A0A2U3X2V9 | A0A2U3WTG3 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. | 0.622 |
IFNG | ICOS | A0A2U3X2V9 | A0A2U3WFU9 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Inducible T-cell costimulator. | 0.690 |
IFNG | IL21 | A0A2U3X2V9 | A0A2U3W0Y3 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin; Belongs to the IL-15/IL-21 family. | 0.841 |
IFNG | IL21R | A0A2U3X2V9 | A0A2U3VQ60 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin-21 receptor. | 0.897 |
IFNG | IL2RG | A0A2U3X2V9 | A0A2U3VNH3 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Cytokine receptor common subunit gamma. | 0.809 |
IFNG | IL6 | A0A2U3X2V9 | A0A2U3VQB3 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin-6 isoform X1. | 0.879 |
IFNG | JAK1 | A0A2U3X2V9 | A0A2U3ZSA9 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Tyrosine-protein kinase. | 0.984 |
IFNG | JAK3 | A0A2U3X2V9 | A0A2U3W8S8 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Tyrosine-protein kinase. | 0.666 |