STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101365189Death domain-containing membrane protein NRADD-like. (250 aa)    
Predicted Functional Partners:
FADD
FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
    
 0.618
KLHL18
Kelch-like protein 18 isoform X1.
      
 0.523
CASP8
Caspase-8 isoform X1; Belongs to the peptidase C14A family.
      
 0.522
PIDD1
P53-induced death domain-containing protein 1.
      
 0.521
LOC101382505
Probable G-protein coupled receptor 148.
  
     0.501
STXBP4
Syntaxin-binding protein 4.
      
 0.472
CDX4
Homeobox protein CDX-4.
      
 0.434
RAPSN
43 kDa receptor-associated protein of the synapse isoform X1.
      
 0.422
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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