STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSMoncostatin-M. (238 aa)    
Predicted Functional Partners:
OSMR
oncostatin-M-specific receptor subunit beta.
    
 0.990
LIFR
Leukemia inhibitory factor receptor.
    
 0.984
IL6ST
Interleukin-6 receptor subunit beta isoform X1.
    
 0.966
CTF1
Cardiotrophin-1 isoform X1.
     
 0.917
JAK1
Tyrosine-protein kinase.
     
 0.915
JAK2
Tyrosine-protein kinase.
     
 0.913
IL11
Interleukin-11.
      
 0.880
LIF
Leukemia inhibitory factor isoform X1.
   
 
 0.858
HGF
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
     
 0.854
IL27RA
Interleukin-27 receptor subunit alpha.
    
 0.820
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.