CCDC24 protein (Odobenus rosmarus) - STRING interaction network

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

CCDC24

Coiled-coil domain-containing protein 24. (310 aa)

Predicted Functional Partners:

RNF220

0.836

RABL2B

0.772

ERI3

0.759

PPAPDC1A

0.597

TIGD5

0.529

PPP4R4

0.524

COPRS

0.524

SMIM14

0.522

SLC25A34

0.522

CCDC62

0.521

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC24	CCDC62	A0A2U3VYW7	A0A2U3VLV0	Coiled-coil domain-containing protein 24.	Coiled-coil domain-containing protein 62 isoform X1.	0.521
CCDC24	COPRS	A0A2U3VYW7	A0A2U3VWD3	Coiled-coil domain-containing protein 24.	Coordinator of PRMT5 and differentiation stimulator isoform X2.	0.524
CCDC24	ERI3	A0A2U3VYW7	A0A2U3VYL0	Coiled-coil domain-containing protein 24.	ERI1 exoribonuclease 3 isoform X1.	0.759
CCDC24	PPAPDC1A	A0A2U3VYW7	A0A2U3W7A6	Coiled-coil domain-containing protein 24.	Phosphatidate phosphatase PPAPDC1A isoform X1.	0.597
CCDC24	PPP4R4	A0A2U3VYW7	A0A2U3VI91	Coiled-coil domain-containing protein 24.	Serine/threonine-protein phosphatase 4 regulatory subunit 4.	0.524
CCDC24	RABL2B	A0A2U3VYW7	A0A2U3WL91	Coiled-coil domain-containing protein 24.	Rab-like protein 2B.	0.772
CCDC24	RNF220	A0A2U3VYW7	A0A2U3VYP8	Coiled-coil domain-containing protein 24.	E3 ubiquitin-protein ligase RNF220.	0.836
CCDC24	SLC25A34	A0A2U3VYW7	A0A2U3VPT5	Coiled-coil domain-containing protein 24.	Solute carrier family 25 member 34; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.522
CCDC24	SMIM14	A0A2U3VYW7	A0A2U3VMD7	Coiled-coil domain-containing protein 24.	Small integral membrane protein 14.	0.522
CCDC24	TIGD5	A0A2U3VYW7	A0A2U3VYR9	Coiled-coil domain-containing protein 24.	Tigger transposable element-derived protein 5.	0.529
CCDC62	CCDC24	A0A2U3VLV0	A0A2U3VYW7	Coiled-coil domain-containing protein 62 isoform X1.	Coiled-coil domain-containing protein 24.	0.521
CCDC62	COPRS	A0A2U3VLV0	A0A2U3VWD3	Coiled-coil domain-containing protein 62 isoform X1.	Coordinator of PRMT5 and differentiation stimulator isoform X2.	0.448
CCDC62	PPAPDC1A	A0A2U3VLV0	A0A2U3W7A6	Coiled-coil domain-containing protein 62 isoform X1.	Phosphatidate phosphatase PPAPDC1A isoform X1.	0.521
CCDC62	PPP4R4	A0A2U3VLV0	A0A2U3VI91	Coiled-coil domain-containing protein 62 isoform X1.	Serine/threonine-protein phosphatase 4 regulatory subunit 4.	0.410
CCDC62	SLC25A34	A0A2U3VLV0	A0A2U3VPT5	Coiled-coil domain-containing protein 62 isoform X1.	Solute carrier family 25 member 34; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.407
COPRS	CCDC24	A0A2U3VWD3	A0A2U3VYW7	Coordinator of PRMT5 and differentiation stimulator isoform X2.	Coiled-coil domain-containing protein 24.	0.524
COPRS	CCDC62	A0A2U3VWD3	A0A2U3VLV0	Coordinator of PRMT5 and differentiation stimulator isoform X2.	Coiled-coil domain-containing protein 62 isoform X1.	0.448
COPRS	PPAPDC1A	A0A2U3VWD3	A0A2U3W7A6	Coordinator of PRMT5 and differentiation stimulator isoform X2.	Phosphatidate phosphatase PPAPDC1A isoform X1.	0.525
COPRS	PPP4R4	A0A2U3VWD3	A0A2U3VI91	Coordinator of PRMT5 and differentiation stimulator isoform X2.	Serine/threonine-protein phosphatase 4 regulatory subunit 4.	0.521
COPRS	SLC25A34	A0A2U3VWD3	A0A2U3VPT5	Coordinator of PRMT5 and differentiation stimulator isoform X2.	Solute carrier family 25 member 34; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.497

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Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.814

expected number of edges:

31

PPI enrichment p-value:

0.42

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009102

Biotin biosynthetic process

4 of 6

2.29

2.43

2.01e-05

GO:0072330

Monocarboxylic acid biosynthetic process

5 of 30

1.68

1.98

2.19e-05

GO:0046394

Carboxylic acid biosynthetic process

6 of 107

1.21

1.17

0.00022

GO:0044281

Small molecule metabolic process

7 of 429

0.67

0.46

0.0126

GO:0071704

Organic substance metabolic process

10 of 1181

0.39

0.28

0.0258

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:36584052

(2022) The inside scoop: Comparative genomics of two intranuclear bacteria, Candidatus Berkiella cookevillensis and Candidatus Berkiella aquae.

4 of 114

1.01

0.78

0.0028

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1111

Biotin metabolic process

4 of 5

2.37

2.7

6.44e-06

CL:1034

Mixed, incl. Vitamin biosynthetic process, and Coenzyme A metabolic process

5 of 45

1.51

1.59

9.73e-05

CL:842

Small molecule biosynthetic process, and Nucleotide biosynthetic process

6 of 141

1.09

0.97

0.00055

CL:1311

Phosphopantetheine, and Fatty acid synthase activity

2 of 5

2.06

0.85

0.0254

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00780

Biotin metabolism

5 of 26

1.75

2.32

3.19e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0093

Biotin biosynthesis

2 of 3

2.29

0.9

0.0221

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