STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCL2L2Bcl-2-like protein 2. (193 aa)    
Predicted Functional Partners:
BCL2L11
Bcl-2-like protein 11 isoform X1.
    
 0.911
BID
BH3-interacting domain death agonist.
   
 0.872
BAD
Bcl2-associated agonist of cell death.
   
 0.856
BAK1
Bcl-2 homologous antagonist/killer.
    
 
0.853
PABPN1
Polyadenylate-binding protein 2.
 
    
 0.791
CASP9
Caspase-9 isoform X1; Belongs to the peptidase C14A family.
   
 0.781
BIK
Bcl-2-interacting killer.
    
 
 0.780
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.770
PMAIP1
Phorbol-12-myristate-13-acetate-induced protein 1.
    
 0.759
BECN1
Beclin-1.
    
 
 0.713
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.