STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF149E3 ubiquitin-protein ligase RNF149. (398 aa)    
Predicted Functional Partners:
ZNF319
Zinc finger protein 319.
    
 
 0.726
UBA2
SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.
   
 
 0.660
JOSD1
Josephin-1.
   
 
 0.621
ZNF207
BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform X1.
      
 0.620
UBE2O
E2/E3 hybrid ubiquitin-protein ligase UBE2O.
   
 0.608
UBE2Z
Ubiquitin-conjugating enzyme E2 Z.
   
 0.608
UBA52
ubiquitin-60S ribosomal protein L40 isoform X1.
    
 0.552
HERC4
Probable E3 ubiquitin-protein ligase HERC4 isoform X1.
    
 0.532
LNX1
E3 ubiquitin-protein ligase LNX isoform X1.
   
 
 0.531
RNF25
E3 ubiquitin-protein ligase RNF25 isoform X1.
      
 0.528
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.