STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBR5E3 ubiquitin-protein ligase UBR5 isoform X1. (2798 aa)    
Predicted Functional Partners:
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X1.
   
  
0.919
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.822
RPS27A
ubiquitin-40S ribosomal protein S27a.
    
 
 0.813
UBA52
ubiquitin-60S ribosomal protein L40 isoform X1.
    
   0.729
SETD2
Histone-lysine N-methyltransferase SETD2.
   
  
 0.711
USP34
Ubiquitin carboxyl-terminal hydrolase 34; Belongs to the peptidase C19 family.
   
  
 0.710
ATMIN
ATM interactor.
    
 
 0.685
UBR2
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.655
EIF4G1
Eukaryotic translation initiation factor 4 gamma 1 isoform X1.
   
   0.646
PAIP1
Polyadenylate-binding protein-interacting protein 1 isoform X1.
   
   0.646
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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