IL1R2 protein (Odobenus rosmarus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

IL1R2

Interleukin-1 receptor type 2. (418 aa)

Predicted Functional Partners:

IL1B

0.996

IL1A

0.994

IL1RN

0.987

IL1R1

0.946

IL1RAP

0.894

IL6R

0.575

IFNAR1

0.567

CCL20

0.549

LOC101373109

0.527

TRAF1

0.505

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL20	IL1A	A0A2U3ZXY8	A0A2U3VWR1	C-C motif chemokine.	Interleukin-1; Belongs to the IL-1 family.	0.787
CCL20	IL1B	A0A2U3ZXY8	A0A2U3VWQ9	C-C motif chemokine.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.821
CCL20	IL1R2	A0A2U3ZXY8	A0A2U3W342	C-C motif chemokine.	Interleukin-1 receptor type 2.	0.549
CCL20	IL1RN	A0A2U3ZXY8	A0A2U3WXR9	C-C motif chemokine.	Interleukin-1.	0.506
IFNAR1	IL1B	A0A2U3WCY9	A0A2U3VWQ9	Interferon alpha/beta receptor 1.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.538
IFNAR1	IL1R2	A0A2U3WCY9	A0A2U3W342	Interferon alpha/beta receptor 1.	Interleukin-1 receptor type 2.	0.567
IL1A	CCL20	A0A2U3VWR1	A0A2U3ZXY8	Interleukin-1; Belongs to the IL-1 family.	C-C motif chemokine.	0.787
IL1A	IL1B	A0A2U3VWR1	A0A2U3VWQ9	Interleukin-1; Belongs to the IL-1 family.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.999
IL1A	IL1R1	A0A2U3VWR1	A0A2U3ZHU4	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1 receptor type 1.	0.987
IL1A	IL1R2	A0A2U3VWR1	A0A2U3W342	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1 receptor type 2.	0.994
IL1A	IL1RAP	A0A2U3VWR1	A0A2U3ZTJ6	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1 receptor accessory protein.	0.972
IL1A	IL1RN	A0A2U3VWR1	A0A2U3WXR9	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.790
IL1B	CCL20	A0A2U3VWQ9	A0A2U3ZXY8	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	C-C motif chemokine.	0.821
IL1B	IFNAR1	A0A2U3VWQ9	A0A2U3WCY9	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interferon alpha/beta receptor 1.	0.538
IL1B	IL1A	A0A2U3VWQ9	A0A2U3VWR1	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1; Belongs to the IL-1 family.	0.999
IL1B	IL1R1	A0A2U3VWQ9	A0A2U3ZHU4	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1 receptor type 1.	0.994
IL1B	IL1R2	A0A2U3VWQ9	A0A2U3W342	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1 receptor type 2.	0.996
IL1B	IL1RAP	A0A2U3VWQ9	A0A2U3ZTJ6	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1 receptor accessory protein.	0.995
IL1B	IL1RN	A0A2U3VWQ9	A0A2U3WXR9	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1.	0.607
IL1B	IL6R	A0A2U3VWQ9	A0A2U3ZJB5	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-6 receptor subunit alpha.	0.527