STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP37Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (979 aa)    
Predicted Functional Partners:
PSMC5
26S protease regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family.
    
 0.759
TRAIP
E3 ubiquitin-protein ligase TRAIP.
  
 
 
 0.673
STAM
Signal transducing adapter molecule 1 isoform X1.
    
 0.610
STAM2
Signal transducing adapter molecule 2 isoform X1.
    
 0.610
MED13
Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
    0.588
ARIH1
RBR-type E3 ubiquitin transferase.
    
 0.565
RPS27A
ubiquitin-40S ribosomal protein S27a.
    
 0.564
UBA52
ubiquitin-60S ribosomal protein L40 isoform X1.
   
 0.542
JOSD2
Josephin-2 isoform X1.
    
 
 0.538
FBXO5
F-box only protein 5.
      
 0.531
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.