STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HBA1Hemoglobin subunit alpha; Belongs to the globin family. (142 aa)    
Predicted Functional Partners:
LOC101369244
Hemoglobin subunit beta-like; Belongs to the globin family.
  
0.997
HBB
Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues.
  
0.997
HP
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
   
 0.991
HBE1
Hemoglobin subunit epsilon; Belongs to the globin family.
  
0.845
LOC101369546
Hemoglobin subunit beta isoform X1; Belongs to the globin family.
  
0.841
LOC101368945
Hemoglobin subunit beta; Belongs to the globin family.
  
0.745
LOC101369845
Hemoglobin subunit epsilon-2; Belongs to the globin family.
  
 
0.692
AHSP
Alpha-hemoglobin-stabilizing protein.
   
 
 0.679
HPX
Hemopexin.
     
 0.651
LOC101385221
Hemoglobin subunit gamma-like; Belongs to the globin family.
   
 0.605
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.