STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)    
Predicted Functional Partners:
GNAS
Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1.
    
 0.999
GNAL
Guanine nucleotide-binding protein G(Olf) subunit alpha isoform X1.
    
 0.959
ADCY6
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
0.958
ADCY3
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
0.956
PRKACA
cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.
    
 0.948
PRKACB
cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily.
    
 0.948
NUDT2
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical].
     
 0.920
RAPGEF4
Rap guanine nucleotide exchange factor 4 isoform X1.
   
 
 0.918
CNR1
Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...]
     
 0.917
RAPGEF3
Rap guanine nucleotide exchange factor 3 isoform X1.
   
 
 0.910
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.