LOC101379524 protein (Odobenus rosmarus) - STRING interaction network

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Score

LOC101379524

Mastin-like. (280 aa)

Predicted Functional Partners:

PRSS58

0.527

LOC101386459

0.517

MST1R

0.505

MET

0.505

LOC101371794

0.489

HP

0.476

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HP	LOC101371794	A0A2U3VF88	A0A2U3W243	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	Chymase isoform X1; Belongs to the peptidase S1 family.	0.485
HP	LOC101379524	A0A2U3VF88	A0A2U3W5D0	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	Mastin-like.	0.476
HP	MET	A0A2U3VF88	A0A2U3WIC3	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	Hepatocyte growth factor receptor.	0.505
HP	MST1R	A0A2U3VF88	A0A2U3VVG3	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	Macrophage-stimulating protein receptor isoform X1.	0.505
HP	PRSS58	A0A2U3VF88	A0A2U3X374	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	Serine protease 58; Belongs to the peptidase S1 family.	0.424
LOC101371794	HP	A0A2U3W243	A0A2U3VF88	Chymase isoform X1; Belongs to the peptidase S1 family.	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	0.485
LOC101371794	LOC101379524	A0A2U3W243	A0A2U3W5D0	Chymase isoform X1; Belongs to the peptidase S1 family.	Mastin-like.	0.489
LOC101371794	MET	A0A2U3W243	A0A2U3WIC3	Chymase isoform X1; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor.	0.505
LOC101371794	MST1R	A0A2U3W243	A0A2U3VVG3	Chymase isoform X1; Belongs to the peptidase S1 family.	Macrophage-stimulating protein receptor isoform X1.	0.505
LOC101379524	HP	A0A2U3W5D0	A0A2U3VF88	Mastin-like.	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	0.476
LOC101379524	LOC101371794	A0A2U3W5D0	A0A2U3W243	Mastin-like.	Chymase isoform X1; Belongs to the peptidase S1 family.	0.489
LOC101379524	LOC101386459	A0A2U3W5D0	A0A2U3ZVM6	Mastin-like.	Probable inactive serine protease 58; Belongs to the peptidase S1 family.	0.517
LOC101379524	MET	A0A2U3W5D0	A0A2U3WIC3	Mastin-like.	Hepatocyte growth factor receptor.	0.505
LOC101379524	MST1R	A0A2U3W5D0	A0A2U3VVG3	Mastin-like.	Macrophage-stimulating protein receptor isoform X1.	0.505
LOC101379524	PRSS58	A0A2U3W5D0	A0A2U3X374	Mastin-like.	Serine protease 58; Belongs to the peptidase S1 family.	0.527
LOC101386459	LOC101379524	A0A2U3ZVM6	A0A2U3W5D0	Probable inactive serine protease 58; Belongs to the peptidase S1 family.	Mastin-like.	0.517
LOC101386459	MET	A0A2U3ZVM6	A0A2U3WIC3	Probable inactive serine protease 58; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor.	0.505
LOC101386459	MST1R	A0A2U3ZVM6	A0A2U3VVG3	Probable inactive serine protease 58; Belongs to the peptidase S1 family.	Macrophage-stimulating protein receptor isoform X1.	0.505
MET	HP	A0A2U3WIC3	A0A2U3VF88	Hepatocyte growth factor receptor.	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	0.505
MET	LOC101371794	A0A2U3WIC3	A0A2U3W243	Hepatocyte growth factor receptor.	Chymase isoform X1; Belongs to the peptidase S1 family.	0.505