STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTSDCathepsin D isoform X1; Belongs to the peptidase A1 family. (410 aa)    
Predicted Functional Partners:
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
   
 0.969
LAMP1
Lysosome-associated membrane glycoprotein 1 isoform X1.
   
 
 0.932
BCL2
Apoptosis regulator Bcl-2.
     
 0.930
BID
BH3-interacting domain death agonist.
   
 
 0.908
BCL2L1
Bcl-2-like protein 1 isoform X1.
     
 0.903
ATP6AP2
Renin receptor isoform X1.
   
 0.880
EEA1
Early endosome antigen 1.
      
 0.872
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 0.871
LAMP2
Lysosome-associated membrane glycoprotein 2 isoform X1.
   
 
 0.862
AGT
Angiotensinogen; Belongs to the serpin family.
   
 0.859
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.