STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MGME1Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA- primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair; Belongs to the MGME1 family. (341 aa)    
Predicted Functional Partners:
LOC101365095
Cytochrome c oxidase assembly factor 7.
      
 0.760
POLG2
DNA polymerase subunit gamma-2, mitochondrial.
      
 0.742
LOC101386392
Lung adenoma susceptibility protein 2 isoform X1.
      
 0.737
GRSF1
G-rich sequence factor 1 isoform X1.
    
 
 0.734
LOC101379201
Uncharacterized protein C3orf14 homolog.
      
 0.724
EXOG
Nuclease EXOG, mitochondrial isoform X1.
      
 0.672
DNA2
DNA replication ATP-dependent helicase/nuclease DNA2.
   
  
 0.641
DONSON
Protein downstream neighbor of Son.
      
 0.618
FBXL4
F-box/LRR-repeat protein 4.
      
 0.616
MTERF4
Transcription termination factor 4, mitochondrial.
      
 0.615
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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