STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101374227Ceruloplasmin; Belongs to the multicopper oxidase family. (1065 aa)    
Predicted Functional Partners:
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
   
 
 0.923
FXN
Frataxin, mitochondrial.
     
 0.919
HMOX2
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
    
 0.911
HMOX1
Heme oxygenase 1.
    
 0.911
LOC101373931
Ceruloplasmin-like; Belongs to the multicopper oxidase family.
  
  
 
0.902
HEPH
Hephaestin isoform X1; Belongs to the multicopper oxidase family.
  
  
 
0.902
SLC40A1
Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
    
 0.837
HP
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
   
 0.776
ATP7B
Copper-transporting ATPase 2 isoform X1.
  
 
 0.772
EDIL3
EGF-like repeat and discoidin I-like domain-containing protein 3 isoform X1.
 
  
 0.766
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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