Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EP300 | ESR1 | A0A2U3VQL3 | A0A2U3ZJE7 | Histone acetyltransferase p300. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.968 |
| EP300 | ESR2 | A0A2U3VQL3 | A0A2U3WKJ7 | Histone acetyltransferase p300. | Estrogen receptor beta isoform X1. | 0.802 |
| EP300 | JUN | A0A2U3VQL3 | A0A2U3WZD8 | Histone acetyltransferase p300. | Transcription factor AP-1 isoform X1; Belongs to the bZIP family. | 0.876 |
| EP300 | MED1 | A0A2U3VQL3 | A0A2U3VJP3 | Histone acetyltransferase p300. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.936 |
| EP300 | NCOA3 | A0A2U3VQL3 | A0A2U3ZKI8 | Histone acetyltransferase p300. | Nuclear receptor coactivator. | 0.981 |
| EP300 | PRKACA | A0A2U3VQL3 | A0A2U3VUI0 | Histone acetyltransferase p300. | cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. | 0.909 |
| EP300 | SP1 | A0A2U3VQL3 | A0A2U3WCQ9 | Histone acetyltransferase p300. | Transcription factor Sp1 isoform X1. | 0.978 |
| EP300 | TBP | A0A2U3VQL3 | A0A2U3ZU18 | Histone acetyltransferase p300. | TATA-box-binding protein. | 0.559 |
| EP300 | TBPL2 | A0A2U3VQL3 | A0A2U3W9H2 | Histone acetyltransferase p300. | TATA box-binding protein-like protein 2. | 0.559 |
| EP300 | TP53 | A0A2U3VQL3 | A0A2U3VT95 | Histone acetyltransferase p300. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.998 |
| ESR1 | EP300 | A0A2U3ZJE7 | A0A2U3VQL3 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Histone acetyltransferase p300. | 0.968 |
| ESR1 | ESR2 | A0A2U3ZJE7 | A0A2U3WKJ7 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Estrogen receptor beta isoform X1. | 0.997 |
| ESR1 | JUN | A0A2U3ZJE7 | A0A2U3WZD8 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Transcription factor AP-1 isoform X1; Belongs to the bZIP family. | 0.983 |
| ESR1 | MED1 | A0A2U3ZJE7 | A0A2U3VJP3 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.985 |
| ESR1 | NCOA3 | A0A2U3ZJE7 | A0A2U3ZKI8 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Nuclear receptor coactivator. | 0.998 |
| ESR1 | PRKACA | A0A2U3ZJE7 | A0A2U3VUI0 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. | 0.942 |
| ESR1 | SP1 | A0A2U3ZJE7 | A0A2U3WCQ9 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Transcription factor Sp1 isoform X1. | 0.988 |
| ESR1 | TBP | A0A2U3ZJE7 | A0A2U3ZU18 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | TATA-box-binding protein. | 0.641 |
| ESR1 | TBPL2 | A0A2U3ZJE7 | A0A2U3W9H2 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | TATA box-binding protein-like protein 2. | 0.501 |
| ESR1 | TP53 | A0A2U3ZJE7 | A0A2U3VT95 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.839 |
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