STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CSKTyrosine-protein kinase. (450 aa)    
Predicted Functional Partners:
PAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1.
    
 0.975
PTPN22
Tyrosine-protein phosphatase non-receptor type 22 isoform X1.
   
 0.974
PXN
Paxillin; Belongs to the paxillin family.
   
 0.973
SRC
Tyrosine-protein kinase.
  
0.970
YES1
Tyrosine-protein kinase.
  
0.802
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.755
CAV1
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
 
 
 0.742
ESR1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
    
 0.718
DOK2
Docking protein 2.
   
 0.716
PTPN12
Tyrosine-protein phosphatase non-receptor type 12 isoform X1.
   
 0.707
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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