SIAH3 protein (Odobenus rosmarus) - STRING interaction network

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SIAH3

E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (267 aa)

Predicted Functional Partners:

SLC52A2

0.662

TOMM7

0.617

CACYBP

0.604

BAG4

0.523

KIAA0408

0.522

DNAJC12

0.521

SLC24A4

0.450

THSD7A

0.450

E2F7

0.443

GMDS

0.442

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAG4	SIAH3	A0A2U3VI14	A0A2U3WIN2	BAG family molecular chaperone regulator 4 isoform X1.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.523
BAG4	TOMM7	A0A2U3VI14	A0A2U3VQA5	BAG family molecular chaperone regulator 4 isoform X1.	Mitochondrial import receptor subunit TOM7 homolog.	0.456
CACYBP	SIAH3	A0A2U3X389	A0A2U3WIN2	Calcyclin-binding protein isoform X1.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.604
DNAJC12	SIAH3	A0A2U3VG93	A0A2U3WIN2	dnaJ homolog subfamily C member 12.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.521
E2F7	SIAH3	A0A2U3W9B9	A0A2U3WIN2	Transcription factor E2F7.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.443
E2F7	SLC52A2	A0A2U3W9B9	A0A2U3VZ19	Transcription factor E2F7.	Solute carrier family 52, riboflavin transporter, member 2.	0.435
GMDS	SIAH3	A0A2U3WI57	A0A2U3WIN2	GDP-mannose 4,6 dehydratase.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.442
KIAA0408	SIAH3	A0A2U3X3Y0	A0A2U3WIN2	Uncharacterized protein KIAA0408 homolog.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.522
SIAH3	BAG4	A0A2U3WIN2	A0A2U3VI14	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	BAG family molecular chaperone regulator 4 isoform X1.	0.523
SIAH3	CACYBP	A0A2U3WIN2	A0A2U3X389	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Calcyclin-binding protein isoform X1.	0.604
SIAH3	DNAJC12	A0A2U3WIN2	A0A2U3VG93	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	dnaJ homolog subfamily C member 12.	0.521
SIAH3	E2F7	A0A2U3WIN2	A0A2U3W9B9	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Transcription factor E2F7.	0.443
SIAH3	GMDS	A0A2U3WIN2	A0A2U3WI57	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	GDP-mannose 4,6 dehydratase.	0.442
SIAH3	KIAA0408	A0A2U3WIN2	A0A2U3X3Y0	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Uncharacterized protein KIAA0408 homolog.	0.522
SIAH3	SLC24A4	A0A2U3WIN2	A0A2U3VI78	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Sodium/potassium/calcium exchanger 4 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.450
SIAH3	SLC52A2	A0A2U3WIN2	A0A2U3VZ19	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Solute carrier family 52, riboflavin transporter, member 2.	0.662
SIAH3	THSD7A	A0A2U3WIN2	A0A2U3VKU2	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Thrombospondin type-1 domain-containing protein 7A.	0.450
SIAH3	TOMM7	A0A2U3WIN2	A0A2U3VQA5	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	Mitochondrial import receptor subunit TOM7 homolog.	0.617
SLC24A4	SIAH3	A0A2U3VI78	A0A2U3WIN2	Sodium/potassium/calcium exchanger 4 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.450
SLC52A2	E2F7	A0A2U3VZ19	A0A2U3W9B9	Solute carrier family 52, riboflavin transporter, member 2.	Transcription factor E2F7.	0.435

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