STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDONCell adhesion molecule-related/down-regulated by oncogenes. (1256 aa)    
Predicted Functional Partners:
PTCH1
Protein patched homolog 1 isoform X1.
    
 0.998
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.993
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.993
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.993
BOC
Brother of CDO isoform X1.
    
0.992
PTCH2
Protein patched homolog 2.
    
 0.961
GAS1
Growth arrest-specific protein 1.
    
 0.936
LRP2
Low-density lipoprotein receptor-related protein 2.
     
 0.912
SMO
Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.845
GLI2
Zinc finger protein GLI2.
    
 0.779
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.