STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCA1ATP-binding cassette sub-family A member 1. (2206 aa)    
Predicted Functional Partners:
APOA1
Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family.
   
 0.993
NR1H2
Oxysterols receptor LXR-beta.
    
 0.867
RXRA
Retinoic acid receptor RXR-alpha isoform X1.
    
 0.817
ZDHHC8
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
 
  0.721
NR1H3
Oxysterols receptor LXR-alpha isoform X1.
    
 0.707
ABCC5
Multidrug resistance-associated protein 5 isoform X1.
  
0.631
APOE
Apolipoprotein E.
      
 0.629
SCARB1
Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family.
   
  
 0.624
PRKACA
cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.
   
 
 0.585
DYNLRB2
Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
   
  
 0.548
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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