STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOX18Transcription factor SOX-18. (387 aa)    
Predicted Functional Partners:
CLDN5
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  
 0.844
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
   
 
 0.732
LYVE1
Lymphatic vessel endothelial hyaluronic acid receptor 1.
   
 0.686
ROBO4
Roundabout homolog 4.
   
  
 0.675
FLT4
Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
  
 0.652
CDH5
Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.642
CCDC85B
Coiled-coil domain-containing protein 85B.
    
 
 0.630
RASIP1
Ras-interacting protein 1 isoform X1.
   
  
 0.597
CTNNB1
Catenin beta-1 isoform X1.
    
 0.584
ZNF358
Zinc finger protein 358.
    
 0.570
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.