STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSMCE2E3 SUMO-protein ligase NSE2. (247 aa)    
Predicted Functional Partners:
NSMCE1
Non-structural maintenance of chromosomes element 1 homolog isoform X1.
    
 0.996
SMC5
Structural maintenance of chromosomes protein 5.
    
 0.996
SMC6
Structural maintenance of chromosomes protein 6.
    
 0.991
NSMCE4A
Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
    
 0.966
EID3
Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
    
 0.966
SMC3
Structural maintenance of chromosomes protein.
    
 0.859
KCTD2
BTB/POZ domain-containing protein KCTD2.
   
 0.852
UBE2I
SUMO-conjugating enzyme UBC9 isoform X1; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.852
SMC1A
Structural maintenance of chromosomes protein.
    
 0.813
SMC1B
Structural maintenance of chromosomes protein.
    
 0.813
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.