STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101376658Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (331 aa)    
Predicted Functional Partners:
HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1.
 
      0.900
TBX5
T-box transcription factor TBX5.
   
  
 0.533
KCNJ2
Inward rectifier potassium channel 2.
      
 0.524
KCNQ1
Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family.
     
 0.455
SYT2
Synaptotagmin-2.
      
 0.446
SYT1
Synaptotagmin-1 isoform X1.
      
 0.446
ATP2B3
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
   
  
 0.441
ASTN1
Astrotactin-1.
      
 0.436
CAV3
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
    
 
 0.414
HCN3
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.
  
 
0.411
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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