OXSR1 protein (Odobenus rosmarus) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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Score

OXSR1

Serine/threonine-protein kinase OSR1 isoform X1. (527 aa)

Predicted Functional Partners:

SEC62

0.871

WNK3

0.760

SEC63

0.746

SEC61B

0.736

WNK4

0.716

SEC61A1

0.690

SEC61A2

0.690

LOC101380501

0.678

LOC101381282

0.678

SEC61G

0.678

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101380501	LOC101381282	A0A2U3W6A8	A0A2U3W933	Protein transport protein Sec61 subunit gamma.	Protein transport protein Sec61 subunit gamma-like.	0.901
LOC101380501	OXSR1	A0A2U3W6A8	A0A2U3WSP4	Protein transport protein Sec61 subunit gamma.	Serine/threonine-protein kinase OSR1 isoform X1.	0.678
LOC101380501	SEC61A1	A0A2U3W6A8	A0A2U3VLN6	Protein transport protein Sec61 subunit gamma.	Protein transport protein Sec61 subunit alpha isoform 1.	0.985
LOC101380501	SEC61A2	A0A2U3W6A8	A0A2U3WK00	Protein transport protein Sec61 subunit gamma.	Protein transport protein Sec61 subunit alpha isoform 2 isoform X1.	0.985
LOC101380501	SEC61B	A0A2U3W6A8	A0A2U3VCT8	Protein transport protein Sec61 subunit gamma.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.996
LOC101380501	SEC61G	A0A2U3W6A8	A0A2U3X2Q2	Protein transport protein Sec61 subunit gamma.	LOW QUALITY PROTEIN: protein transport protein Sec61 subunit gamma.	0.900
LOC101380501	SEC62	A0A2U3W6A8	A0A2U3VFG1	Protein transport protein Sec61 subunit gamma.	Translocation protein SEC62.	0.790
LOC101380501	SEC63	A0A2U3W6A8	A0A2U3VRR9	Protein transport protein Sec61 subunit gamma.	Translocation protein SEC63 homolog isoform X1.	0.904
LOC101381282	LOC101380501	A0A2U3W933	A0A2U3W6A8	Protein transport protein Sec61 subunit gamma-like.	Protein transport protein Sec61 subunit gamma.	0.901
LOC101381282	OXSR1	A0A2U3W933	A0A2U3WSP4	Protein transport protein Sec61 subunit gamma-like.	Serine/threonine-protein kinase OSR1 isoform X1.	0.678
LOC101381282	SEC61A1	A0A2U3W933	A0A2U3VLN6	Protein transport protein Sec61 subunit gamma-like.	Protein transport protein Sec61 subunit alpha isoform 1.	0.985
LOC101381282	SEC61A2	A0A2U3W933	A0A2U3WK00	Protein transport protein Sec61 subunit gamma-like.	Protein transport protein Sec61 subunit alpha isoform 2 isoform X1.	0.985
LOC101381282	SEC61B	A0A2U3W933	A0A2U3VCT8	Protein transport protein Sec61 subunit gamma-like.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.996
LOC101381282	SEC61G	A0A2U3W933	A0A2U3X2Q2	Protein transport protein Sec61 subunit gamma-like.	LOW QUALITY PROTEIN: protein transport protein Sec61 subunit gamma.	0.901
LOC101381282	SEC62	A0A2U3W933	A0A2U3VFG1	Protein transport protein Sec61 subunit gamma-like.	Translocation protein SEC62.	0.790
LOC101381282	SEC63	A0A2U3W933	A0A2U3VRR9	Protein transport protein Sec61 subunit gamma-like.	Translocation protein SEC63 homolog isoform X1.	0.904
OXSR1	LOC101380501	A0A2U3WSP4	A0A2U3W6A8	Serine/threonine-protein kinase OSR1 isoform X1.	Protein transport protein Sec61 subunit gamma.	0.678
OXSR1	LOC101381282	A0A2U3WSP4	A0A2U3W933	Serine/threonine-protein kinase OSR1 isoform X1.	Protein transport protein Sec61 subunit gamma-like.	0.678
OXSR1	SEC61A1	A0A2U3WSP4	A0A2U3VLN6	Serine/threonine-protein kinase OSR1 isoform X1.	Protein transport protein Sec61 subunit alpha isoform 1.	0.690
OXSR1	SEC61A2	A0A2U3WSP4	A0A2U3WK00	Serine/threonine-protein kinase OSR1 isoform X1.	Protein transport protein Sec61 subunit alpha isoform 2 isoform X1.	0.690

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.968

expected number of edges:

11

PPI enrichment p-value:

3.84e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006525

Arginine metabolic process

11 of 34

2.23

8.23

2.82e-21

GO:0006526

Arginine biosynthetic process

9 of 17

2.45

8.04

4.90e-18

GO:0006591

Ornithine metabolic process

4 of 6

2.55

3.56

1.65e-07

GO:0042450

Arginine biosynthetic process via ornithine

2 of 2

2.72

1.57

0.0014

GO:0044205

De novo UMP biosynthetic process

2 of 7

2.18

1.12

0.0079

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0103045

Methione N-acyltransferase activity

2 of 2

2.72

0.93

0.0203

GO:0004088

Carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

2 of 2

2.72

0.93

0.0203

GO:0004042

acetyl-CoA:L-glutamate N-acetyltransferase activity

2 of 2

2.72

0.93

0.0203

GO:0016774

Phosphotransferase activity, carboxyl group as acceptor

2 of 7

2.18

0.82

0.0303

GO:0016879

Ligase activity, forming carbon-nitrogen bonds

3 of 51

1.49

0.73

0.0303

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 1829

0.5

0.42

0.00052

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1505

Arginine biosynthesis, and Amino acid antiporter

9 of 15

2.5

8.22

4.37e-18

CL:1510

Arginine biosynthesis

6 of 6

2.72

6.12

1.70e-12

CL:1367

Cellular amino acid biosynthetic process, and Ribonucleoside monophosphate biosynthetic process

11 of 152

1.58

3.6

3.78e-15

CL:1525

Amino acid antiporter, and Arginine catabolic process to ornithine

2 of 5

2.33

1.03

0.0127

CL:1578

Pyrimidine biosynthesis, and Dihydroorotase, conserved site

2 of 6

2.25

0.99

0.0148

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pfn00220

Arginine biosynthesis

9 of 36

2.12

6.25

3.12e-16

pfn00250

Alanine, aspartate and glutamate metabolism

4 of 39

1.74

1.95

3.78e-05

pfn01230

Biosynthesis of amino acids

7 of 179

1.32

1.75

6.17e-07

pfn01210

2-Oxocarboxylic acid metabolism

4 of 51

1.62

1.75

6.84e-05

pfn01110

Biosynthesis of secondary metabolites

8 of 614

0.84

0.78

6.84e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005951

Carbamoyl-phosphate synthase complex

2 of 2

2.72

1.18

0.0073

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0055

Arginine biosynthesis

9 of 13

2.56

8.87

2.96e-19

KW-0963

Cytoplasm

8 of 311

1.13

1.38

8.14e-07

KW-0665

Pyrimidine biosynthesis

2 of 10

2.03

1.0

0.0124

KW-0436

Ligase

3 of 73

1.34

0.8

0.0152

KW-0808

Transferase

5 of 407

0.81

0.51

0.0216

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00696

Amino acid kinase family

3 of 6

2.42

1.85

0.00035

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036393

Acetylglutamate kinase-like superfamily

3 of 6

2.42

1.71

0.00065

IPR001048

Aspartate/glutamate/uridylate kinase

3 of 6

2.42

1.71

0.00065

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