STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101364543L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)    
Predicted Functional Partners:
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.945
ME2
Malic enzyme.
  
 0.933
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.922
LDHD
Probable D-lactate dehydrogenase, mitochondrial.
   
 
 0.915
GPI
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.893
GOT2
Aspartate aminotransferase.
   
 0.860
H6PD
GDH/6PGL endoplasmic bifunctional protein.
  
 
 0.849
G6PD
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
   
 
 0.847
TALDO1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 0.838
PKLR
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.836
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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