STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa)    
Predicted Functional Partners:
SGMS1
Phosphatidylcholine:ceramide cholinephosphotransferase 1.
     
 0.978
SGMS2
Phosphatidylcholine:ceramide cholinephosphotransferase 2.
     
 0.976
UGCG
Ceramide glucosyltransferase.
     
 0.969
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.960
GBA
Glucosylceramidase.
   
 
 0.956
SMPD3
Sphingomyelin phosphodiesterase 3 isoform X1.
     
 0.954
SMPD4
Sphingomyelin phosphodiesterase 4 isoform X1.
     
 0.951
CERK
Ceramide kinase.
    
 0.951
GBA2
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
     
 0.950
CERS6
Ceramide synthase 6 isoform X1.
     
 0.950
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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