STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GFRA1GDNF family receptor alpha-1 isoform X1. (535 aa)    
Predicted Functional Partners:
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.992
GDNF
Glial cell line-derived neurotrophic factor isoform X1.
    
 0.980
KIT
Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.802
NRTN
LOW QUALITY PROTEIN: neurturin.
    
 0.748
UCHL1
Ubiquitin carboxyl-terminal hydrolase.
   
  
 0.723
NCAM1
Neural cell adhesion molecule 1 isoform X1.
    
 0.710
NANOS2
Nanos homolog 2; Belongs to the nanos family.
      
 0.687
ETV5
ETS translocation variant 5 isoform X1.
      
 0.684
FGFR1
Fibroblast growth factor receptor.
    
 0.653
FGFRL1
Fibroblast growth factor receptor-like 1.
    
 0.653
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.