STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP1LC3CMicrotubule-associated proteins 1A/1B light chain 3C. (169 aa)    
Predicted Functional Partners:
NBR1
Next to BRCA1 gene 1 protein.
   
 0.979
MAP1LC3B
Microtubule-associated proteins 1A/1B light chain 3B isoform X1.
  
  
 
0.942
MAP1LC3A
Microtubule-associated proteins 1A/1B light chain 3A.
  
  
 
0.941
CALCOCO2
Calcium-binding and coiled-coil domain-containing protein 2 isoform X1.
   
 0.891
ATG3
Autophagy-related protein 3.
   
 0.860
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
   
 0.839
ATG4B
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.
   
 0.800
ATG5
Autophagy protein 5; Involved in autophagic vesicle formation.
   
 0.768
PLEKHM1
LOW QUALITY PROTEIN: pleckstrin homology domain-containing family M member 1.
    
 
 0.765
SQSTM1
Sequestosome-1.
   
 0.763
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.