STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM86ALOW QUALITY PROTEIN: lysoplasmalogenase-like protein TMEM86A. (356 aa)    
Predicted Functional Partners:
ASNA1
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
      
 0.754
LHFPL2
Lipoma HMGIC fusion partner-like 2 protein.
      
 0.657
TSPAN2
Tetraspanin.
      
 0.621
ADAMTS3
A disintegrin and metalloproteinase with thrombospondin motifs 3.
   
  
 0.620
VIPR1
Vasoactive intestinal polypeptide receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family.
      
 0.616
TMEM51
Transmembrane protein 51.
      
 0.615
FBLIM1
Filamin-binding LIM protein 1 isoform X1.
      
 0.527
TSPAN14
Tetraspanin.
      
 0.527
CYTIP
Cytohesin-interacting protein.
      
 0.526
SNX24
Sorting nexin-24.
      
 0.524
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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