STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)    
Predicted Functional Partners:
IFNGR1
Interferon gamma receptor 1.
  
 
 0.999
IFNGR2
LOW QUALITY PROTEIN: interferon gamma receptor 2.
    
 0.989
JAK2
Tyrosine-protein kinase.
   
 
 0.984
JAK1
Tyrosine-protein kinase.
   
 
 0.984
IFNAR1
Interferon alpha/beta receptor 1.
     
 0.971
IL10
Interleukin-10.
   
  
 0.950
IFNAR2
Interferon alpha/beta receptor 2.
  
 
 0.946
FOXP3
Forkhead box protein P3 isoform X1.
   
 0.944
PSME1
Proteasome activator complex subunit 1 isoform X1.
   
 
 0.938
PSME2
Proteasome activator complex subunit 2 isoform X1.
   
 
 0.932
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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