STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIM1Single-minded homolog 1. (766 aa)    
Predicted Functional Partners:
MC4R
Melanocortin receptor 4.
      
 0.838
AGRP
Agouti-related protein.
      
 0.802
TRH
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
      
 0.762
ARNT2
Aryl hydrocarbon receptor nuclear translocator 2.
    
 
0.758
POMC
Pro-opiomelanocortin.
   
  
 0.722
ARNT
Aryl hydrocarbon receptor nuclear translocator isoform X1.
    
 
0.672
NPY
Pro-neuropeptide Y.
      
 0.615
MCHR2
Melanin-concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.614
BSX
Brain-specific homeobox protein homolog.
      
 0.614
OTP
Homeobox protein orthopedia.
   
  
 0.544
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.