TREM1 protein (Odobenus rosmarus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TREM1

Triggering receptor expressed on myeloid cells 1. (238 aa)

Predicted Functional Partners:

TYROBP

0.900

TREML1

0.694

TREML2

0.652

PGLYRP1

0.643

IL1B

0.640

CCL1

0.619

APP

0.614

CD300A

0.600

AQP9

0.585

TREM2

0.582

Your Current Organism:

Odobenus rosmarus

NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	IL1B	A0A2U3WVA3	A0A2U3VWQ9	Amyloid beta A4 protein isoform X1.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.523
APP	TREM1	A0A2U3WVA3	A0A2U3X4D7	Amyloid beta A4 protein isoform X1.	Triggering receptor expressed on myeloid cells 1.	0.614
APP	TREM2	A0A2U3WVA3	A0A2U3X4C9	Amyloid beta A4 protein isoform X1.	Triggering receptor expressed on myeloid cells 2.	0.485
APP	TREML1	A0A2U3WVA3	A0A2U3X4Q9	Amyloid beta A4 protein isoform X1.	Trem-like transcript 1 protein isoform X1.	0.485
AQP9	TREM1	A0A2U3WE97	A0A2U3X4D7	Aquaporin-9; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Triggering receptor expressed on myeloid cells 1.	0.585
CCL1	IL1B	A0A2U3X472	A0A2U3VWQ9	C-C motif chemokine 1.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.491
CCL1	TREM1	A0A2U3X472	A0A2U3X4D7	C-C motif chemokine 1.	Triggering receptor expressed on myeloid cells 1.	0.619
CD300A	TREM1	A0A2U3ZH85	A0A2U3X4D7	CMRF35-like molecule 8.	Triggering receptor expressed on myeloid cells 1.	0.600
CD300A	TREM2	A0A2U3ZH85	A0A2U3X4C9	CMRF35-like molecule 8.	Triggering receptor expressed on myeloid cells 2.	0.402
CD300A	TREML1	A0A2U3ZH85	A0A2U3X4Q9	CMRF35-like molecule 8.	Trem-like transcript 1 protein isoform X1.	0.402
CD300A	TYROBP	A0A2U3ZH85	A0A2U3VN63	CMRF35-like molecule 8.	TYRO protein tyrosine kinase-binding protein isoform X1.	0.604
IL1B	APP	A0A2U3VWQ9	A0A2U3WVA3	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Amyloid beta A4 protein isoform X1.	0.523
IL1B	CCL1	A0A2U3VWQ9	A0A2U3X472	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	C-C motif chemokine 1.	0.491
IL1B	TREM1	A0A2U3VWQ9	A0A2U3X4D7	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Triggering receptor expressed on myeloid cells 1.	0.640
IL1B	TREM2	A0A2U3VWQ9	A0A2U3X4C9	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Triggering receptor expressed on myeloid cells 2.	0.474
IL1B	TREML1	A0A2U3VWQ9	A0A2U3X4Q9	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Trem-like transcript 1 protein isoform X1.	0.474
PGLYRP1	TREM1	A0A2U3VZL4	A0A2U3X4D7	Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity.	Triggering receptor expressed on myeloid cells 1.	0.643
TREM1	APP	A0A2U3X4D7	A0A2U3WVA3	Triggering receptor expressed on myeloid cells 1.	Amyloid beta A4 protein isoform X1.	0.614
TREM1	AQP9	A0A2U3X4D7	A0A2U3WE97	Triggering receptor expressed on myeloid cells 1.	Aquaporin-9; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.585
TREM1	CCL1	A0A2U3X4D7	A0A2U3X472	Triggering receptor expressed on myeloid cells 1.	C-C motif chemokine 1.	0.619