STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMX3Protein disulfide-isomerase TMX3. (453 aa)    
Predicted Functional Partners:
EMC6
ER membrane protein complex subunit 6.
      
 0.743
GSR
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.660
TMX4
Thioredoxin-related transmembrane protein 4.
   
 
 0.648
MSRA
Mitochondrial peptide methionine sulfoxide reductase isoform X1.
   
 0.607
TMX2
Thioredoxin-related transmembrane protein 2 isoform X1.
    
 
 0.589
DNAJC5
dnaJ homolog subfamily C member 5.
    
 
 0.570
ERGIC3
Endoplasmic reticulum-Golgi intermediate compartment protein 3 isoform X1.
  
 
 0.533
PRDX5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.527
CCDC109B
Calcium uniporter regulatory subunit MCUb, mitochondrial.
      
 0.526
TXNDC15
Thioredoxin domain-containing protein 15.
      
 0.524
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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