STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101372264LOW QUALITY PROTEIN: cytochrome P450 2D15. (491 aa)    
Predicted Functional Partners:
LOC101367833
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
  
 
 0.954
LOC101378904
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Belongs to the 3-beta-HSD family.
   
 0.933
STS
Steryl-sulfatase.
   
 
 0.921
LOC101384623
Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.
  
0.920
LOC101379669
Aldo-keto reductase family 1 member C1 homolog.
   
 
 0.912
LOC101377633
Aldo-keto reductase family 1 member C3-like.
   
 
 0.911
SULT2B1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
 
 0.908
LOC101375846
Cytochrome P450 3A12-like.
  
 0.663
TM7SF2
Delta(14)-sterol reductase isoform X1.
   
 0.592
LOC101384815
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
  
 
 0.592
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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